In adynamic bone disease, intact PTH is less than what value?

In adynamic bone disease, intact PTH is less than what value?

• A. > 300 pg/mL
• B. 250 pg/mL
• C. < 150 pg/mL
• D. < 50 pg/mL

Answer: (C)

Adynamic bone disease is a low-turnover bone disorder seen in dialysis patients when bone remodeling is suppressed by too-low PTH levels. The key sign is that intact PTH is low, typically below about 150 pg/mL. That level signals reduced osteoblast/osteoclast activity and minimal bone turnover, which fits the concept of adynamic bone disease. Higher PTH values (around 250–300 pg/mL or more) indicate high-turnover bone disease, while extremely low values like 50 pg/mL are not the threshold used to define ABD in this context. Therefore, a PTH under 150 pg/mL best identifies adynamic bone disease.

Adynamic bone disease is a low-turnover bone disorder seen in dialysis patients when bone remodeling is suppressed by too-low PTH levels. The key sign is that intact PTH is low, typically below about 150 pg/mL. That level signals reduced osteoblast/osteoclast activity and minimal bone turnover, which fits the concept of adynamic bone disease. Higher PTH values (around 250–300 pg/mL or more) indicate high-turnover bone disease, while extremely low values like 50 pg/mL are not the threshold used to define ABD in this context. Therefore, a PTH under 150 pg/mL best identifies adynamic bone disease.